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COPD with elevated sputum group 2 innate lymphoid cells is characterized by severe disease [J

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Klein Geltink RI, OSullivan D, Corrado M, Bremser A, Buck MD, Buescher JM, et al

[DOI] [PubMed] [Google Scholar] Gilmore JH, Jarskog LF

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MDSCs are marked by elevated glutaminolytic flux compared to other myeloid cells, as they facilitate the upregulation of immunosuppressive mediators (ARG1, iNOS, and PD-L1) via HIF-1-mTORC1 activation (60)